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In some embodiments, following the isolation of the microspheres from the continuous-phase processing medium, the remainder of the solvent in the microspheres is removed by extraction

Whats more, SESN2 activation by oxidative stress occurs through multiple upstream signals, including p53, nuclear factor erythroid 2related factor2 (Nrf2), CCAAT-enhancer-binding protein (c/EBP), and Hypoxia-Inducible Factor 1 (HIF-1) [30,31,32,33]

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